Department : Division of Medical Engineering

Drug Delivery Agents for Prevention or Treatment of Pulmonary Disease, 폐질환용 약물전달체 (특허출원 2018. 06. 01, PCT 출원 2019.05.27)
Remote Drug Injection System, 약물 원격 투약 시스템 및 그것의 제어 방법 (특허출원 10-2017-0011661, 2017.01.25)
Injection Kit and Control System, 주사용 키트 및 그의 제어 방법 (특허출원 10-2016-0047691, 2016.04.19, 특허등록 2018.06.21.)
Drug Delivery Control System (나노입자 약물 전달 장치 및 그의 제어 방법) (특허출원 10-2016-0013133, 2016.02.02, 특허등록 2017.08.23.)
Discoidal Polymeric Nanoconstructs and Methods of Use in Cancer Theranostics (WO2015176025, PCT/US2015/031226)

[국외논문]

• Jun Young Park*, Sanghyo Park*, Tae Sup Lee, Yong Hwa Hwang, Jung Young Kim, Won Jun Kang, Jaehong Key, "Biodegradable micro-sized discoidal polymeric particles for lung targeted delivery system", Biomaterials, 218, 119331, 2019 (Impact Factor: 10.273)
• Susmita Aryal, Hyungkyu Park, James F. Leary, Jaehong Key, “Top-down fabrication-based nano/microparticles for molecular imaging and drug delivery”, International Journal of Nanomedicine, 14, 6631–6644, 2019 (Impact Factor: 4.370)
• Ye Ji Ahn, Tae Hoon Kong, Jin Sil Choi, Wan Su Yoon, Jaehong Key, and Young Joon Seo, “Strategies to Enhance Efficacy of SPION-Labeled Stem Cell Homing by Magnetic Attraction: A Systemic Review with Meta-Analysis”, International Journal of Nanomedicine, 14, 4849–4866, 2019 (Impact Factor: 4.370)
• Sanghyo Park, Hyungkyu Park, Seokhyeon Jeong, Bong Gu Yi, Kyeong Soon Park and Jaehong Key, "Hyaluronic Acid Conjugated Mesoporous Silica Nanoparticles Loaded with Dual Anticancer Agents for Chemo-Photodynamic Cancer Therapy", Journal of Nanomaterials, Volume 2019, Article ID 3481397, 11 pages, 2019 (Impact Factor: 2.207)
• Tuyen Duong Thanh Nguyen§, Susmita Aryal§, Arunkumar Pitchaimani, Sanghyo Park, Jaehong Key*, Santosh Aryal*,"Biomimetic Surface Modification of Discoidal Polymeric Particles", Nanomedicine: Nanotechnology, Biology, and Medicine, 16, 79-87, 2019 (Impact Factor: 6.500)
• S. Choi, K. Ko, J. Lim, S.-H. Kim, S.-H. Woo, Y. S. Kim, J. Key, S. Y. Lee, I. S. Park, S. W. Lee, "Non-Linear Cellular Dielectrophoretic Behavior Characterization Using Dielectrophoretic Tweezers-Based Force Spectroscopy inside a Microfluidic Device", Sensors, 18(10), 3543:1-10, 2018 (Impact Factor: 2.475)
• Wan Su Yun, Jin Sil Choi, Hyun Mi Ju, Min Hee Kim, Seong Jin Choi, Eun Seol Oh, Young Joon Seo, Jaehong Key, "Enhanced Homing Technique of Mesenchymal Stem Cells using Iron Oxide Nanoparticles by Magnetic Attraction in Olfactory-Injured Mouse Model", International Journal of Molecular Sciences, 2018 (Impact Factor: 4.183)
• AeJu Lee, Sung Hoon Kim, Hyun Lee, Bohee Kim, Yoon Suk Kim, and Jaehong Key, "Visualization of MMP-2 Activity Using Dual-Probe Nanoparticles to Detect Potential Metastatic Cancer Cells", Nanomaterials 8, 119, 2018 (Impact Factor: 3.553)
• Young‑Jin Jung, Taewoo Lee, Seungyeop Choi, Sei‑Young Lee, Jaehong Key, Yeong‑Min Yoo, Woo‑Jin Chang, Han‑Sung Kim, Sang Woo Lee, "Selective position of individual cells without lysis on a circular window array using dielectrophoresis in a microfluidic device", Microfluid Nanofluid 21:150, 2017 (Impact Factor: 2.344)
• Minjung Cho, Antonio Cervadoro, Maricela R. Ramirez, Cinzia Stigliano, Audrius Brazdeikis, Vicki L. Colvin, Pierluigi Civera, Jaehong Key* and Paolo Decuzzi*, “Assembly of Iron Oxide Nanocubes for Enhanced Cancer Hyperthermia and Magnetic Resonance Imaging”, Nanomaterials, 7(4), 72, 2017 (Impact Factor: 3.553)
• Cinzia Stigliano, Maricela R. Ramirez, Jaykrishna V. Singh, Santosh Aryal, Jaehong Key, Elvin Blanco, Paolo Decuzzi, “Methotraxate-Loaded Hybrid Nanoconstructs Target Vascular Lesions and Inhibit Atherosclerosis Progression in ApoE−/− Mice”, Advanced Healthcare Materials, 1601286, 2017 (Impact Factor: 5.110)

[국내논문]

• Do Hoon Kwakǂ, Woo Cheol Kimǂ, Hee Won Jin, Wan Su Yun, Sanghyo Park, Jaehong Key, “Study on the Cell Adhesion of Breast Cancer Cells using Nano/Micro Patterning PDMS”, Journal of Biomedical Engineering Research, accepted, 2019
• Junyoung Parkǂ, Sanghyo Parkǂ, Yerim Jo, Minji Jeong, Inwoo Kim, Wonjun Kang and Jaehong Key, "Study of Lipid Coated Polymeric Nanoparticles for Lung Metastasis", Journal of Biomedical Engineering Research 39: 147-152, 2018
• Inwoo Kim, Seungbin Park, Yuhyun Ji, Sanghyo Park and Jaehong Key, "The Biostability and Cancer Effect of PLGA Nanoparticles with Different Charges", Journal of Biomedical Engineering Research 39: 140-145, 2018
• Chongmyeong Leeǂ, Hyeonho Hanǂ, Byonghan Jang, Eunseol Oh, Jaehong Key, "Nanoparticle Inducing Device for Effective Drug Delivery System", Journal of Biomedical Engineering Research 38:102-110, 2017
• J.Y. Bae, E.S. Oh, H.J. Ahn, J.H. Key “Assessment of Discoidal Polymeric Nanoconstructs as a Drug Carrier”, Journal of Biomedical Engineering Research, 38:43-48, 2017
• J.Y. Bae, E.S. Oh, H. Lee and J.H. Key, "Improved Manufacturing Method of Discoidal Nanoparticles for Cancer Theranostics", Journal of Biomedical Engineering Research 37:46-52, 2016
• Arunkumar Pitchaimani, Tuyen Duong Thanh Nguyen, Leila Maurmann, Jaehong Key, Stefan H. Bossmann, Santosh Aryal,“Gd3+ Tethered Gold Nanorods for Combined Magnetic Resonance Imaging and Photo-Thermal Therapy”, Journal of Biomedical Nanotechnology, 13(4):417-426, 2017 (Impact Factor: 4.521)
• Jaehong Key and Kyeongsoon Park, “Multicomponent, Tumor-Homing Chitosan Nanoparticles for Cancer Imaging and Therapy”, International Journal of Molecular Sciences, 18, 594, 2017 (Impact Factor: 3.226)
• J.H. Yoon, D.K. Kim, J. Key, S.W. Lee and S.Y. Lee, "Adhesion characteristics of nano/micro sized particle with multiple ligands with different interaction distance", RSC Advances, 6, 89785-89793, 2016 (Impact Factor: 3.289)
• Jaehong Key, Deepika Dhawan, Christy L. Cooper, Deborah W. Knapp, Kwangmeyung Kim, Ick Chan Kwon, Kuiwon Choi, Kinam Park, Paolo Decuzzi, James F. Leary, "Multicomponent, peptide-targeted glycol chitosan nanoparticles containing ferrimagnetic iron oxide nanocubes for bladder cancer multimodal imaging", International Journal of Nanomedicine, 11, 4141-4155, 2016 (Impact Factor: 4.300)