[주요경력]
진단검사의학 전공의, 연세의대 세브란스병원
전임강사, 연세의대 세브란스병원
조교수, 연세의대 세브란스병원
부교수, 연세의대 세브란스병원

[기타경력]
연세대학교 박사 (의학)
미국국립보건원 (NIH), Post-doctor fellowship
University of Washing Medicine, Tumor Vaccine Group, 방문교수
Harvard Medical School, Mesachuesset General Hospital, 방문교수

연세의대 졸업
연세대학교 석사 (의학)
연세대학교 박사 (의학)

[강의]
임상화학
임상면역학
자동화 검사실 운영
Cancer immunotherapyTumor micro-metastasis mechanism
Circulating Tumor cell,
Epithelial-Mesenchymal Transition

[논문]

• Park Q, Lim JB, Yi KS, Kim MJ, Kim HO, Song KS. Platelet Transfusion Support for Splenectomy in Patients with Chronic Immune Thrombocytopenic Purpura. Korean J Blood Transfusion 9:201-8, 1998
• Lim JB, Kim MJ, Yi KS, Lee SM, Kim HO. Evaluation of the Collection Efficiency of the Granulocyte in Leukapheresis Using 10% Pentastarch. Korean J Clin Pathol 19: 125-30, 1999
• Lim JB, Kim HS, Park Q, Lee SK, Park YB, Han CT. Clinical Significance of Anti-HSP 70 Antibody in Patients with Systemic Lupus Erythematosus. Korean J Clinical Pathol 19: 548-53,1999
• Yi KS, Lim JB, Kim HK, Park Q, Song KS, Kim KY. A Case of Glanzmann’s Thrombasthenia with Unusual Platelet Aggregation Response. Korean J Hemostasis Thromb 6:131-36,1999
• Lyu CJ, Park SH, Cho HS, Kim HO, Lim JB, Park SM, Yang CH, Kim KY, Cho JS, Park YW. Method of RBC Depletion from Human Umbilical Cord Blood. Korean J Ped Hematol Oncol 5:163-70, 1998
• Chong Y, Lee K, Shin JW, Shin HB, Lim JB. Activity of Arbekacin Against Methicillin-resistant Staphylococcus Aureus and Pseudomonas Aeruginosa. J Korean Society Chemoth 15:319-27, 1997
• Kim MJ, Lee SM, Lim JB, Yi KS, Park Q, Kim HO, Song KS. Determining the Optimal Time for Peripheral Blood Stem Cell Harvest by Detecting Immature Cells using Hematology Analyzer, SE-9000TM IMI Channel. Korea J Clin Pathol 4:252-57, 1999
• Lee K, Shin JW, Lim JB, Kim YA, Yong D, Oh HB, Chong Y. Emerging antimicrobial resistance, plasmid profile and pulsed-field gel electrophoresis pattern of the endonuclease-digested genomic DNA of Neisseria gonorrhoeae. Yonsei Med J 41(3):381-6, 2000
• Lee K, Lim JB, Yum JH, Yong D, Chong Y, Kim JM, Livermore DM. bla(VIM-2) cassette-containing novel integrons in metallo-beta-lactamase-producing Pseudomonas aeruginosa and Pseudomonas putida isolates disseminated in a Korean hospital. Antimicrob Agents Chemother 2002;46:1053-8
• Kim HS, Lim JB, Min YH, Lee ST, Lyu CJ, Kim ES, Kim HO. Ex Vivo Expansion of Human Umbilical Cord Blood CD34+ Cells in a Collagen Bead-Containing 3-Dimensionla Culture System. Int J Hematol 2003;78:126-132
• Provenzano M, Lim JB, Mocellin S, Monsurro V, Bettinotti M, Marincola FM, Stroncek DF. The matrix protein pp65(341-350): a peptide that induces ex vivo stimulation and in vitro expansion of CMV-specific CD8+ T cells in subjects bearing either HLA-A*2402 or A*0101 allele. Transfusion. 2003 Nov; 43(11): 1567-74
• Dittmar K, Lim JB, Caruccio L, Bettinotti M, Stroncek D. Assessment of the relative number of copies of the gene encoding human neutrophil antigen-2a (HNA-2a), CD177, and a homologous pseudogene by quantitative real-time PCR. Immunohematology 2003:19;122-126.
• Slota M, Lim JB, Dang Y, Disis ML. ELISpot for measuring human immune responses to vaccines.. Expert Rev Vaccines. 2011 Mar;10(3):299-306.
• Chung HW, Jang S, Lim JB. Clinical implications and diagnostic usefulness of correlation between soluble major histocompatibility complex class I chain-related molecule a and protumorigenic cytokines in pancreatic ductal adenocarcinoma. Cancer. 2012 Jun 26.
• Adoptive immunotherapy for Cytomegalovirus (CMV) disease in immunocompromised patientsYONSEI MEDICAL JOURNAL 45/ :18-22,2004
• CMV 질환의 면역치료법 개발에 대한 최신지견건국의과학학술지(The Konkuk Journal. Of Medical Sciences) 13/2 :-,2004
• PREG-Qtm를 이용한 체외임신반응검사의 임상적 유용성 평가임상검사와 정도관리 26/1 :207-210,2004
• Effectiveness of real-time quantitative PCR compare to repeat PCR for the diagnosis of Charcot-Marie-Tooth type 1A and hereditary neuropathy with liability to pressure palsiesYONSEI MEDICAL JOURNAL 46/3 :347-352,2005
• TDM검사 신빙도조사 결과보고(2004)임상검사와 정도관리 27/1 :111-124,2005
• Identification of HLA-A33-restricted CMV pp65 epitopes as common targets for CD8EXPERIMENTAL HEMATOLOGY 34/ :296-307,2006
• TDM검사 신빙도조사 결과보고(2005)임상검사와 정도관리 28/1 :121-134,2006
• 유지 혈액투석 환자에서 단기간의 빈혈 개선에 따른 혈중 Amino-Terminal Pro B-type NatriureticPeptide (NT-pro BNP)치 및 심초음파 소견의 변화The Korean Journal of Nephrology 25/5 :803-811,2006
• TDM검사 신빙도조사 결과보고(2006)임상검사와 정도관리 29/1 :121-135,2007
• 다양한 신질환을 가진 소아에서 Cystatin C 검사의임상적 유용성대한소아신장학회지 11/2 :161-167,2007
• TDM 및 약물남용검사 신빙도조사 결과보고(2007)임상검사와 정도관리(Journal of Laboratory Medicine and Quality Assurance) 30/1 :133-149,2008
• Cytokine Profile of Peripheral Blood in Type 2 Diabetes Mellitus Patients with Diabetic RetinopathyAnnals Of Clinical And Laboratory Science 38/ :361-367,2008
• Comparison of the Validity of Three Biomarkers for Gastric Cancer Screening Carcinoembryonic Antigen, Pepsinogens, and High Sensitive C-reactive ProteinJournal Of Clinical Gastroenterology 43/1 :19-26,2009
• Effect of Intravitreal Bevacizumab Injection on Aqueous Humor Cytokine Levels in Clinically Significant Macular EdemaOphthalmology 116/ :80-86,2009
• Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancerJournal of Translational Medicine 7/ :38-48,2009
• Expression of interleukin-5 and tumor necrosis factor alpha in cervical carcinomaClinical And Vaccine Immunology 16/6 :959-961,2009
• Concentration of cytokines in the aqueous humor of patients with naive, recurrent and regressed cnv associated with amd after bevacizumab treatmentRetina-The Journal Of Retinal And Vitreous Diseases 29/4 :523-529,2009
• Radiosensitization Effect of STI-571 on Pancreatic Cancer Cells In VitroINTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 75/3 :862-869,2009
• Identification of HLA-A*2402-restricted HCMV immediate early-1 (IE-1) epitopes as targets for CD8+HCMV-specific cytotoxic T lymphocytesJournal of Translational Medicine 7/1 :72-83,2009
• Functional Recovery After the Transplantation of Neurally Differentiated Mesenchymal Stem Cells Derived From Bone Barrow in a Rat Model of Spinal Cord InjuryCell Transplantation 18/12 :1359-1368,2009
• Outbreak by meropenem-resistant Pseudomonas aeruginosa producing IMP-6 metallo-β-lactamase in a Korean hospitalDiagnostic Microbiology And Infectious Disease 63/1 :115-117,2009
• Axillary Lymph Node Metastasis: CA-15-3 and Carcinoembryonic Antigen Concentrations in Fine-Needle Aspirates for Preoperative Diagnosis in Patients with Breast CancerRADIOLOGY 254/ :691-697,2010
• Analysis of demographic characteristics in 3242 young age gastric cancer patients in KoreaWORLD JOURNAL OF GASTROENTEROLOGY 16/2 :256-263,2010
• Panel of Candidate Biomarkers for Renal Cell CarcinomaJournal of Proteome Research 9/7 :3710-3719,2010
• Development of a serum-free medium for in vitro expansion of human cytotoxic T lymphocytes using a statistical designBmc Biotechnology 10/ :70-70,2010
• Concentration of cytokines in age-related macular degeneration after consecutive intravitreal bevacizumab injectionGRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 248/5 :635-640,2010
• Clinical significance of serum levels of immune-associated molecules, uric acid and soluble MHC class I chain-related molecules A and B, as diagnostic tumor markers for pancreatic ductal adenocarcinomaCANCER SCIENCE 102/9 :1673-1679,2011
• ELISpot for measuring human immune responses to vaccinesEXPERT REVIEW OF VACCINES 10/3 :299-306,2011
• Cell-to-Cell Contact with Hepatitis C Virus-Infected Cells Reduces Functional Capacity of Natural Killer CellsJOURNAL OF VIROLOGY 85/23 :12557-12569,2011
• Identification of novel immunogenic human leukocyte antigen-A*2402- binding epitopes of human papillomavirus type 16 E7 for immunotherapy against human cervical cancerCANCER 118/8 :2173-2183,2012
• Serum high mobility group box-1 is a powerful diagnostic and prognostic biomarker for pancreatic ductal adenocarcinomaCANCER SCIENCE 103/9 :1714-1721,2012
• clinical implications and diagnostic usefulness of correlation between soluble major Histocompatibility Complex Class I Chain-Related Molecule A and Protumorigenic Cytokines in Pancreatic Ductal AdenocarcinomaCANCER 119/1 :233-244,2013
• Composite Three-Marker Assay for Early Detection of Kidney CancerCANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 22/3 :390-398,2013
• Clinical significance of elevated serum soluble CD40 ligand levels as a diagnostic and prognostic tumor marker for pancreatic ductal adenocarcinoma.JOURNAL OF TRANSLATIONAL MEDICINE 12/1 :1-9,2014
• Identification of Novel Epitopes From Human Papillomavirus Type 18 E7 That Can Sensitize PBMCs of Multiple HLA class I Against Human Cervical CancerJOURNAL OF TRANSLATIONAL MEDICINE 12/1 :229-,2014
• Clinical significance of serum thymus and activation-regulated chemokine in gastric cancer: Potential as a serum biomarkerCANCER SCIENCE 105/10 :1327-1333,2014
• Role of the tumor microenvironment in the pathogenesis of gastric carcinomaWORLD JOURNAL OF GASTROENTEROLOGY 20/Issue :1667-1680,2014
• Clinical significance and usefulness of soluble heparin binding-epidermal growth factor in gastric cancerWORLD JOURNAL OF GASTROENTEROLOGY 21/7 :2080-2088,2015
• Serum ENA78/CXCL5, SDF-1/CXCL12, and their combinations as potential biomarkers for prediction of the presence and distant metastasis of primary gastric cancerCYTOKINE 73/1 :16-22,2015
• Combined targeting of high-mobility group box-1 and interleukin-8 to control micrometastasis potential in gastric cancerINTERNATIONAL JOURNAL OF CANCER 137/7 :1598-1609,2015
• HbA1c for diagnosis and prognosis of gestational diabetes mellitusDIABETES RESEARCH AND CLINICAL PRACTICE 110/1 :38-43,2015
• CD4(+) T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than DeletionIMMUNITY 43/5 :896-908,2015
• Ascorbate Oxidase Minimizes Interference by High-Concentration Ascorbic Acid in Total Cholesterol AssaysANNALS OF LABORATORY MEDICINE 36/26 :188-190,2016
• Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy.YONSEI MEDICAL JOURNAL 58/1 :43-50,2017
• Homeostasis model assessment of insulin resistance in a general adult population in Korea: additive association of sarcopenia and obesity with insulin resistanceCLINICAL ENDOCRINOLOGY 86/1 :44-51,2017
• High-mobility group box-1 contributes tumor angiogenesis under interleukin-8 mediation during gastric cancer progressionCANCER SCIENCE 108/8 :1594-1601,2017
• A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric CancerYONSEI MEDICAL JOURNAL 60/8 :713-719,2019